Projects

Sequence programming, Image reconstruction, fMRI

SMS-EPI fMRI

A Pulseq SMS-EPI fMRI sequence and reconstruction protocol, suitable for multi-site, multi-vendor studies.

Sequence programming, Image reconstruction, Diffusion

Pulseq-diffusion

MatLab code to create diffusion EPI sequences to be run using the Pulseq sequence programming environment

Sequence programming, Image reconstruction, fMRI, Diffusion

High-resolution multi-shot readout-segmented EPI

This is a open source project for a ISMRM 2024 abstract and its submitted MRM paper under review. It is a high-resolution multi-shot readout-segmented EPI sequence with shot-to-shot phase fluctuations estimated from overlapped k-space regions between segments, instead of relying on external 2D navigators. The scripts include Pulseq sequence generation, example data, and reconstruction script, all in MATLAB. I aim to have a associated link available for the ISMRM diffusion workshop 2025 (ddl. submission Dec 6th 2024), and later a few modifications are expected to improve its user-friendliness.

Quantitative MRI

Rapid, open-source, cross-platform 3D multiparametric mapping for multisite neuroimaging

Open-source, vendor-agnostic, rapid 3D multiparametric mapping provided T1 and T2 relaxation times with less than a 4.0% variation across different scanners, software, and vendors, with improved cross-vendor reproducibility for both in phantom and in vivo data compared to vendor-native implementations.

Sequence programming, Pulseq interpreter

Pulseq on GE v2

Community-developed Pulseq interpreter for GE scanners.

Sequence programming

Pypulseq

Python-based, vendor-neutral pulse sequence programming

Sequence programming, Image reconstruction, Image processing, Quantitative MRI

Free-breathing fat quantification with flip angle modulation

This project implements a flip angle modulated, 2D-encoded sequential Cartesian gradient echo acquisition for high-SNR, motion-robust fat (PDFF) and iron (R2*) quantification, originally designed for use in the liver. After confounder-corrected fitting for PDFF and R2*, initial results show strong reproducibility across vendors, scanner models, and field strengths.

Sequence programming, Image reconstruction, Diffusion

PRIME: Phase Reversed Interleaved Multi-Echo acquisition enables highly accelerated distortion-free diffusion MRI

Phase-reversed interleaved multi-echo acquisition (PRIME) for rapid, high-resolution, and distortion-free dMRI

Sequence programming, Image reconstruction, Quantitative MRI

MIMOSA: Multi-parametric Imaging using Multiple-echoes with Optimized Simultaneous Acquisition for highly-efficient quantitative MRI

MIMOSA enables highly-efficient T1, T2, T2*, PD, QSM, para- and diamagnetic susceptibility mapping.