Projects

Sequence programming, Image reconstruction, Diffusion

Pulseq-diffusion

MatLab code to create diffusion EPI sequences to be run using the Pulseq sequence programming environment

Quantitative MRI

Rapid, open-source, cross-platform 3D multiparametric mapping for multisite neuroimaging

Open-source, vendor-agnostic, rapid 3D multiparametric mapping provided T1 and T2 relaxation times with less than a 4.0% variation across different scanners, software, and vendors, with improved cross-vendor reproducibility for both in phantom and in vivo data compared to vendor-native implementations.

Sequence programming, Pulseq interpreter

Pulseq on GE

Community-developed Pulseq interpreter for GE scanners.

Sequence programming

Pypulseq

Python-based, vendor-neutral pulse sequence programming

Sequence programming, Image reconstruction, Image processing, Quantitative MRI

Free-breathing fat quantification with flip angle modulation

This project implements a flip angle modulated, 2D-encoded sequential Cartesian gradient echo acquisition for high-SNR, motion-robust fat (PDFF) and iron (R2*) quantification, originally designed for use in the liver. After confounder-corrected fitting for PDFF and R2*, initial results show strong reproducibility across vendors, scanner models, and field strengths.

Sequence programming, Image reconstruction, Diffusion

PRIME: Phase Reversed Interleaved Multi-Echo acquisition enables highly accelerated distortion-free diffusion MRI

Phase-reversed interleaved multi-echo acquisition (PRIME) for rapid, high-resolution, and distortion-free dMRI

Sequence programming, Image reconstruction, Quantitative MRI

MIMOSA: Multi-parametric Imaging using Multiple-echoes with Optimized Simultaneous Acquisition for highly-efficient quantitative MRI

MIMOSA enables highly-efficient T1, T2, T2*, PD, QSM, para- and diamagnetic susceptibility mapping.

Sequence programming

Shuffle3DGRE

An open (via Pulseq) 3D gradient echo MRI sequence supporting multiple Cartesian trajectory options for reducing physiological fluctuation artifacts

Sequence programming, Image reconstruction, fMRI

Fast-fMRI: Random 3D-EPI Acquisition + Locally Low-Rank Reconstruction

A set of tools for vendor-agnostic, highly accelerated fMRI acquisition and reconstruction.

Sequence programming

Open-MOLLI

Open-source Myocardial T1 mapping (Open-MOLLI) developed using Pulseq is an inversion recovery T1 mapping sequence with a triggering scheme 5(3)3. Open-MOLLI provides the groundwork for standardization and for further developments such as adding simultaneous multi-slice excitation (SMS) capabilities to Open-MOLLI myocardium T1 mapping.

Sequence programming, Image reconstruction

Looping Star

Looping Star pulse sequence and reconstruction pipeline in Pulseq

Sequence programming, Image reconstruction, Image processing, Simulations, Protocol workflow, Diffusion, Quantitative MRI

OpenMRF

A Pulseq-based Magnetic Resonance Fingerprinting Framework

Sequence programming, Image reconstruction, fMRI

Functional MRI protocols in Pulseq

Harmonized fMRI sequences and reconstruction protocols for multi-site, multi-vendor studies.

Sequence programming, Protocol workflow

Pulsepal - Pulseq AI Assistant

Pulsepal is an AI agent with access to Pulseq documentation, function signatures, and complete sequences. This allows Pulsepal to answer questions, provide tutorials, assist with coding, and help debug Pulseq MATLAB code. Pulsepal has a familiar feel to other LLMs, such as GPT and Gemini, but specialized and focused for Pulseq knowledge.

Sequence programming

Multi-Echo Stack of Stars

An open-source and vendor-agnostic 3D multi-echo stack-of-stars sequence implemented in Pulseq

Sequence programming, Image reconstruction, fMRI, Diffusion

Overlap-Kernel EPI

A Pulseq demo of seq. and recon. for multi-shot 2D EPI with 4 trajectories and self-navigation options.